Semler Scientific has reported an unrealized loss of around $41.8 million on its Bitcoin holdings for Q1 2025, following a 12% drop in BTC prices during the period. As of March 31, the company held 3,182 BTC valued at approximately $263.5 million. Despite this loss, Semler is moving ahead with a plan to sell up to $500 million in securities , aiming to use some of the funds to buy more Bitcoin. The healthcare tech firm also revealed expected quarterly revenues of $8.8 to $8.9 million and operating losses of up to $1.5 million. It held about $10 million in cash and is also negotiating a nearly $30 million settlement with the U.S. Department of Justice over a civil investigation. Semler, currently the twelfth-largest corporate Bitcoin holder, remains firm in its crypto strategy, saying the proceeds from the stock sale will support both general operations and continued BTC purchases.